Fact Sheet

SMRV - Virus Testing

Interest Group

Pharmaceutical industry, media manufacturer, Research and Development, cell banks, cell line development.

Description

Two-stage test service for Squirrel Monkey Retrovirus (SMRV): cells are screened for SMRV DNA and only positive cell lines are subsequently examined for active virus by direct test (RT-PCR).

Recommended Sample Material

Cell cultures supernatants with cells.

Method

Conventional PCR and RT-PCR.

Applied PCR System

In-house.

Applied Extraction

QiaAMP DSP Virus Spin Kit (Qiagen AG), QiaAMP DSP Virus Kit (Qiagen AG) and ExtractNow DNA/RNA Kit (Minerva Biolabs GmbH).

Process Control

Extraction and Amplification.

Sample Volume / PCR

5 µl.

Average Turnaround Time

48 to 72 hours after sample receipt, express testing scheme* possible.

Sensitivity of Method

Based on sample matrix.

Regulatory Compliance

Please note that the sensitivity of the assay regarding your matrix may need to be validated. Please contact us for further information.

Sample Requirements

Inactivated (Screen), Native (Direct Test).
Minimum: at least 1.5 ml. 
Optimum: 2 units of 1.5 ml each, label as sample A and sample B (backup, please mark in accession form).

Order No.

Virus Testing ‘SMRV Screen’                46-2001
Virus Testing ‘SMRV Direct Test’         46-2002

Volume Discount Available

Yes, on request.

Additional Information

Please note: repetitions which are not caused by our laboratory and *express testing schemes are subject to additonal charges. Please contact us for further information.